Micro-Raman Spectroscopy for Monitoring Changes in Periodontal Ligaments and Gingival Crevicular Fluid

Micro-Raman Spectroscopy for Monitoring Changes in Periodontal Ligaments and Gingival Crevicular Fluid

Micro-Raman Spectroscopy is an efficient method for analyzing biological specimens due to its sensitivity to subtle chemical and structural changes. The aim of this study was to use micro-Raman spectroscopy to analyze chemical and structural changes in periodontal ligament after orthodontic force application and in gingival crevicular fluid in presence of periodontal disease. The biopsy of peri...

Gingival Crevicular Fluid Biomarkers

Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...

Oral Fluid-Based Biomarkers in Periodontal Disease – Part 2. Gingival Crevicular Fluid

Periodontal diagnosis and treatment plan are based on the assessment of probing depth, clinical attachment level, plaque index, gingival index, bleeding on probing, suppuration, furcation involvement, mobility, and radiographic findings. However, these clinical parameters are not sufficiently sensitive and specific to identify disease activity in individual sites or to predict future attachment...

Hydroxyproline titers in gingival crevicular fluid.

Salivary and gingival crevicular fluid histatin in periodontal health and disease

OBJECTIVES Histatin, with its anti bacterial, anti protease, and wound closure stimulating property might influence the pathogenesis of periodontal disease. This study assessed the presence of histatin in gingival crevicular fluid (GCF); the levels of salivary and GCF histatin in periodontal disease. MATERIAL AND METHODS It was a cross sectional study that included systemically healthy forty ...